Search resultsDrink to prevent: Review on the cardioprotective mechanisms of alcohol and red wine polyphenols
Title
Drink to prevent: Review on the cardioprotective mechanisms of alcohol and red wine polyphenols
Publication type
Journal Article
Year of Publication
2004
Authors
Journal
Seminars in Vascular Medicine
Volume
4
Issue
2
Pagination
173 - 186
Date published
2004
ISBN
15289648 (ISSN)
Keywords
alcohol, alcohol consumption, Alcohol Drinking, antioxidant activity, Antioxidants, blood clotting, Cardiovascular Diseases, cardiovascular risk, cholesterol blood level, Cholesterol, HDL, Ethanol, fibrinolysis, Flavonoids, heart protection, high density lipoprotein cholesterol, human, Humans, ischemic heart disease, lipid blood level, Lipids, nitric oxide, Phenols, plasminogen activator inhibitor 1, Platelet aggregation, polyphenol derivative, polyphenols, red wine, review, risk assessment, thrombocyte, thrombosis, thromboxane A2, wine
Abstract
Moderate alcohol consumption has convincingly been associated with decreased cardiovascular mortality in epidemiological studies and metaanalyses. This decreased mortality has been attributed to changes in lipid profiles, decreased coagulation, increased fibrinolysis, inhibition of platelets, increased nitric oxide, and antioxidant capacities of alcoholic beverages. Most of these laboratory and animal studies, as well as small intervention trials in human volunteers, have revealed many interesting mechanisms that contribute to the cardioprotective effects of alcohol, red wine, or red wine polyphenolic compounds. An update on putative mechanisms is presented in this review.