Does diet affect breast cancer risk?
Title
Does diet affect breast cancer risk?
Publication type
Journal Article
Year of Publication
2004
Authors
Journal
Breast Cancer Research
Volume
6
Issue
4
Pagination
170 - 178
Date published
2004
ISBN
14655411 (ISSN)
Keywords
alcohol consumption, alpha tocopherol, Animals, antioxidant, ascorbic acid, beta carotene, breast cancer, Breast Neoplasms, caffeine, caloric intake, cancer mortality, cancer risk, carbohydrate, carbohydrate intake, carcinogen, daidzin, diet, dietary fiber, disease association, energy balance, Estradiol, estrogen, estrogen receptor, Ethanol, fat intake, feeding behavior, fruit, genistein, glucose, glucose blood level, human, Humans, isoflavone derivative, life event, monounsaturated fatty acid, nonhuman, obesity, phytoestrogen, polyunsaturated fatty acid, postmenopause, receptor binding, retinol, review, saturated fatty acid, selenium, tamoxifen, vegetable, weight gain, women
Abstract
The role of specific dietary factors in breast cancer causation is not completely resolved. Results from prospective studies do not support the concept that fat intake in middle life has a major relation to breast cancer risk. However, weight gain in middle life contributes substantially to breast cancer risk. Alcohol is the best established dietary risk factor, probably by increasing endogenous estrogen levels. Hypotheses relating diet during youth to risk decades later will be difficult to test. Nevertheless, available evidence is strong that breast cancer risk can be reduced by avoiding weight gain during adult years, and by limiting alcohol consumption.