High-density lipoproteins: Effects of alcohol, estrogen, and phytoestrogens

Title
High-density lipoproteins: Effects of alcohol, estrogen, and phytoestrogens
Publication type
Journal Article
Year of Publication
2002
Journal
Nutrition Reviews
Volume
60
Issue
1
Pagination
1 - 7
Date published
2002
ISBN
00296643 (ISSN)
Abstract
Plasma high-density lipoproteins (HDL) play an important role in the reverse cholesterol transport pathway. Factors affecting plasma HDL levels may be important, therefore, in the prevention of cardiovascular disease. Among the lifestyle and environmental factors that have been shown to increase HDL cholesterol are moderate alcohol intake and estrogen administration. Phytoestrogens, molecules of plant origin that resemble estrogen and act as weak estrogens, do not have a clear effect on HDL cholesterol. The molecular mechanisms of action of alcohol, estrogen, and phytoestrogens on HDL are under investigation.