Search resultsEpigenetics and lifestyle
Title
Epigenetics and lifestyle
Publication type
Journal Article
Year of Publication
2011
Authors
Journal
Epigenomics
Volume
3
Issue
3
Pagination
267 - 277
Date published
2011
ISBN
17501911 (ISSN)
Keywords
air pollution, alcohol, alcohol consumption, Alcohol Drinking, antineoplastic activity, arsenic, benzene, black carbon, cancer cell culture, cancer risk, choline, cigarette smoking, circadian rhythm, colorectal cancer, cyanocobalamin, diet, dietary intake, DNA, DNA metabolism, DNA methylation, DNA methyltransferase, DNA modification, drug mechanism, emotional stress, Environmental Exposure, environmental exposures, environmental factor, Environmental Pollutants, epigallocatechin gallate, Epigenesis, Genetic, epigenetics, Exercise, folic acid, Folic Acid Deficiency, gamma interferon, gene silencing, Gene-Environment Interaction, genistein, glucocorticoid receptor, health, histone modifications, human, Humans, in vitro study, in vivo study, Life Style, lifestyle, lung cancer, mental stress, methionine, Motor Activity, Nicotiana tabacum, nonhuman, nutrition, nutritional status, obesity, organic compound, organic pollution, oxidative stress, particulate matter, persistent organic pollutant, physical activity, phytoestrogen, pollutant, polycyclic aromatic hydrocarbon, polyphenol derivative, priority journal, promoter region, pyridoxine, recommended drug dose, review, risk factor, s adenosylmethionine, sedentary lifestyle, selenium, shift worker, smoking, soybean, stomach carcinoma, Stress, Psychological, tobacco smoke, transcription factor CLOCK, tumor necrosis factor alpha, work
Abstract
The concept of lifestyle includes different factors such as nutrition, behavior, stress, physical activity, working habits, smoking and alcohol consumption. Increasing evidence shows that environmental and lifestyle factors may influence epigenetic mechanisms, such as DNA methylation, histone acetylation and miRNA expression. It has been identified that several lifestyle factors such as diet, obesity, physical activity, tobacco smoking, alcohol consumption, environmental pollutants, psychological stress and working on night shifts might modify epigenetic patterns. Most of the studies conducted so far have been centered on DNA methylation, whereas only a few investigations have studied lifestyle factors in relation to histone modifications and miRNAs. This article reviews current evidence indicating that lifestyle factors might affect human health via epigenetic mechanisms.