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A meta-analysis of alcohol consumption and the risk of gout

Title
A meta-analysis of alcohol consumption and the risk of gout
Publication type
Journal Article
Year of Publication
2013
Authors
Wang, M., Jiang, X., Wu, W., Zhang, D.
Journal
Clinical Rheumatology
Volume
32
Issue
11
Pagination
1641 - 1648
Date published
2013
ISBN
07703198 (ISSN)
Keywords
alcohol consumption, Alcohol Drinking, alcoholic beverage, article, Asia, Caucasian, drinking behavior, ethnicity, follow up, gout, human, Humans, meta analysis, meta-analysis, observational study, prevalence, primary prevention, priority journal, Risk, risk factor
Abstract
Alcohol consumption had been linked to the risk of gout theoretically, but the results from observational studies were conflicting. Hence, a meta-analysis was conducted to assess the effect of alcohol consumption on the risk of gout. A comprehensive search was performed to identify all eligible studies on the association of alcohol consumption with gout risk. Pooled relative risks (RRs) with 95 % confidence intervals (CIs) from fixed and random effects models were calculated. A total of 12 articles with 17 studies involving 42,924 cases met the inclusion criteria. The pooled RR for highest vs. non/occasional alcohol drinking in every study was 1.98 (95 % CI, 1.52-2.58). The RRs for light (≤1 drink/day), moderate (>1 to <3 drinks/day), and heavy drinking (≥3 drinks/day) vs. non/occasional alcohol drinking were 1.16 (95 % CI, 1.07-1.25), 1.58 (95 % CI, 1.50-1.66), and 2.64 (95 % CI, 2.26-3.09), respectively. The results suggested that alcohol consumption might be associated with increased risk of gout.
DOI
https://dx.doi.org/10.1007/s10067-013-2319-y
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