Alcohol intake and risk of rosacea in US women

Alcohol intake and risk of rosacea in US women
Publication type
Journal Article
Year of Publication
Journal of the American Academy of Dermatology
Date published

Background: The epidemiologic association between alcohol and rosacea is unclear and inconsistent based on the previous cross-sectional or case-control studies. Objective: We conducted a cohort study to determine the association between alcohol intake and the risk of rosacea in women. Methods: A total of 82,737 women were included from the Nurses' Health Study II (1991-2005). Information on alcohol intake was collected every 4 years during follow-up. Information on history of clinician-diagnosed rosacea and year of diagnosis was collected in 2005. Results: Over 14 years of follow-up, we identified 4945 cases of rosacea. Compared with never drinkers, increased alcohol intake was associated with a significantly increased risk of rosacea (P trend <.0001). The multivariate-adjusted hazard ratios (HRs) and confidence intervals (CIs) were 1.12 (95% CI 1.05-1.20) for alcohol intake of 1-4 g/day and 1.53 (1.26-1.84) for ≥30 g/day. The associations remained consistent across categories of smoking status. Further examination of types of alcoholic beverage consumed revealed that white wine (P trend <.0001) and liquor intake (P trend = .0006) were significantly associated with a higher risk of rosacea. Limitations: This was an epidemiologic study without examination into etiologic mechanisms. Conclusions: Alcohol intake was significantly associated with an increased risk of rosacea in women.