Alcoholic beverage preference and diabetes incidence across Europe: the Consortium on Health and Ageing Network of Cohorts in Europe and the United States (CHANCES) project
Abstract
Background/Objectives: It is unknown if wine, beer, and spirit intake lead to a similar association with diabetes. We studied the association between alcoholic beverage preference and type 2 diabetes incidence in persons who reported to consume alcohol.
Subjects/Methods: Ten European cohort studies from the Consortium on Health and Ageing: Network of Cohorts in Europe and the United States (CHANCES) were included, comprising participant data of 62 458 adults who reported alcohol consumption at baseline. Diabetes incidence was based on documented and/or self-reported diagnosis during follow-up. Preference was defined as ≥70% of total alcohol consumed was either beer, wine or spirits. Adjusted hazard ratios (HRs) were computed using Cox proportional hazard regression. Single cohort HRs were pooled by random-effects meta-analysis.
Results: Beer, wine, or spirit preference was not related to diabetes risk compared with having no preference. The pooled HRs were HR 1.06 (95%CI 0.93, 1.20) for beer, HR 0.99 (95%CI 0.88, 1.11) for wine, and HR 1.19 (95%CI 0.97, 1.46) for spirit preference. Absolute wine intake, adjusted for total alcohol, was associated with a lower diabetes risk: pooled HR per 6 grams/day was 0.96 (95% CI 0.93, 0.99). A spirit preference was related to a higher diabetes risk in those with a higher BMI, in men and women separately, but not after excluding persons with prevalent diseases
Conclusions: This large individual-level meta-analysis among persons who reported alcohol consumption revealed that the preference for beer, wine, and spirits was similarly associated with diabetes incidence compared with having no preference.