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Effects of silicon, fluoride, etidronate and magnesium on bone mineral density: a retrospective study.

Title
Effects of silicon, fluoride, etidronate and magnesium on bone mineral density: a retrospective study.
Publication type
Journal Article
Year of Publication
1993
Authors
Eisinger, J., Clairet, D.
Journal
Magnesium research : official organ of the International Society for the Development of Research on Magnesium
Volume
6
Issue
3
Pagination
247 - 249
Date published
1993
ISBN
09531424 (ISSN)
Keywords
Adult, Aged, article, bone density, drug effect, etidronic acid, Female, fluoride, Fluorides, human, magnesium, Middle age, Osteoporosis, Postmenopausal, pathophysiology, postmenopause osteoporosis, Retrospective Studies, retrospective study, silicon
Abstract
A retrospective study of bone mineral density (BMD) changes was performed in 53 osteoporotic women prior to carrying out a prospective study. Comparisons between BMD of controls (n = 16) and treated groups over a 14-22 month period showed that fluoride (n = 10) induced a significant (P < 0.05) increase in vertebral and a slight decrease in femoral BMD, whereas silicon (n = 8) induced a significant (P < 0.05) increase in femoral BMD. Etidronate (n = 13) and, to a lesser extent, magnesium (n = 6), induced a slight although statistically non-significant increase in vertebral BMD.
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