Search resultsRelationship between alcohol habits and hemorheology by a micro channel method in a general population
Title
Relationship between alcohol habits and hemorheology by a micro channel method in a general population
Publication type
Journal Article
Year of Publication
2008
Authors
Journal
Clinical Cardiology
Volume
31
Issue
11
Pagination
488 - 491
Date published
2008
ISBN
01609289 (ISSN)
Keywords
Adult, age, alcohol, article, Biosocial factors, blood pressure, blood rheology, body mass, cardiovascular disease, device, diagnostic value, drinking behavior, Female, gender, hematocrit, human, human experiment, Japanese, leukocyte count, lifestyle, lipid blood level, low density lipoprotein cholesterol, Low-density lipoprotein, male, normal human, physical activity, Preventive cardiology, smoking habit, statistical analysis
Abstract
Background: Hemorheology plays an important role in the development of cardiovascular disease. The Micro Channel array Flow Analyzer (MC-FAN) (Hitachi Haramachi Electronics Co., Ltd., Bentencho, Japan) is currently considered a useful new device to analyze hemorheology. However, the relationships between various lifestyle habits and hemorheology, especially using MC-FAN, have still not been thoroughly investigated. Hypothesis: The study was undertaken to determine whether there could be some correlations of lifestyle factors to hemorheology by MC-FAN. Methods: A total of 250 asymptomatic Japanese subjects (male:female=100:150; mean age=49.7 y) without any medication were enrolled in the present study. Hemorheology was assessed by the whole blood passage time (WBPT) and was corrected by the saline passage time using MC-FAN. Subjects' lifestyle factors, such as smoking habits, alcohol habits, and physical activity, were self-reported. Results: Partial correlation analysis for WBPT, after controlling for age, gender, hematocrit, white blood cell count, body mass index, blood pressure, blood biochemical measures, and all lifestyle habits, revealed a significant and inverse correlation between alcohol habits of 1-3 go (amount of alcohol intake) and WBPT (r = -0.191, p = 0.003), in addition to a significant positive correlation between serum low-density lipoprotein (LDL) cholesterol and WBPT. Conclusions: These data suggest that alcohol habits may beneficially affect hemorheology by MC-FAN, expanding the protective effect of light-to-moderate alcohol consumption against cardiovascular disease.