Alcohol consumption and circulating markers of inflammation
Title
Alcohol consumption and circulating markers of inflammation
Publication type
Journal Article
Year of Publication
2005
Authors
Journal
Recenti Progressi in Medicina
Volume
96
Issue
2
Pagination
102 - 107
Date published
2005
ISBN
00341193 (ISSN)
Keywords
alcohol, alcohol consumption, Alcohol Drinking, atherosclerosis, biological marker, Biological Markers, blood, C reactive protein, C-Reactive Protein, C-RP, cardiovascular risk, cause of death, cytokine, Cytokines, drinking behavior, Ethanol, fibrinogen, human, Humans, IL-6, Immunology, immunomodulation, inflammation, interleukin 6, Interleukin-6, mortality, review, risk factor
Abstract
Atherosclerosis, the leading cause of death in western countries, is a multifactiorial condition in which a local and low-grade inflammatory response plays an important role. Elevation in markers of inflammation prospectively defines risk of atherosclerotic complications and predicts all-cause mortality. Alcohol consumption has been related with all-cause mortality and cardiovascular risk with a J-shaped relationship, suggesting that alcohol consumption might have an antiinflammatory effect. This review assesses the current state of knowledge regarding the immunomodulatory effect of moderate alcohol consumption.