Search resultsEffects of alcohol consumption on female fertility during an 18-year period
Title
Effects of alcohol consumption on female fertility during an 18-year period
Publication type
Journal Article
Year of Publication
2004
Authors
Journal
Fertility and Sterility
Volume
81
Issue
2
Pagination
379 - 383
Date published
2004
ISBN
00150282 (ISSN)
Keywords
Adolescent, Adult, alcohol, alcohol consumption, Alcohol Drinking, article, correlation analysis, delivery, ectopic pregnancy, endometriosis, Female, female fertility, female infertility, fertility, hospitalization, human, Humans, induced abortion, infertility, Infertility examination, Infertility, Female, Life style factor, major clinical study, Middle Aged, pelvic inflammatory disease, Pregnancy, Pregnancy Complications, Pregnancy outcome, Pregnancy, Ectopic, priority journal, questionnaire, spontaneous abortion, statistical significance, Sweden
Abstract
Objective: To investigate the long-term effects of alcohol consumption on female fertility. Design: Prospective study of a random sample of 7,393 women, selected from the 445,000 inhabitants of Stockholm County, Sweden, in 1969. Self-estimated alcohol consumption was obtained from postal questionnaires. Data on hospitalizations for pregnancy outcomes including infertility examinations were analyzed until 1987. Setting: Healthy women in Stockholm County, Sweden. Patient(s): Seven thousand three hundred ninety-three women in the age range 18-28 years. Main Outcome Measure(s): Rates of hospitalization for deliveries, miscarriages, legal abortions, extrauterine pregnancies, pelvic inflammatory disease, endometriosis, and infertility examinations were analyzed in relation to the intake of alcohol. Result(s): Two hundred fifty-two women underwent infertility examinations. High consumers had an increased risk for such examinations, as compared with moderate consumers: relative risk ratio (RR) = 1.59 (95% confidence interval [CI]: 1.09-2.31); and low consumers had a decreased risk (RR = 0.64; CI: 0.46-0.90). Moreover, for both high and low consumers we observed a significantly lower number of first and second partus. Rates of miscarriage, extrauterine pregnancy, and pelvic inflammatory disease did not differ between high and low consumers of alcohol. Conclusion(s): High alcohol consumption was associated with increased risk of infertility examinations at hospitals and with lower numbers of first and second partus. It may be important for the female partner in an infertile couple to limit alcohol intake or to not drink at all.