Search resultsAlcohol consumption and mortality in Japan: The Miyagi Cohort Study
Title
Alcohol consumption and mortality in Japan: The Miyagi Cohort Study
Publication type
Journal Article
Year of Publication
2004
Authors
Journal
Journal of Epidemiology
Volume
14
Issue
SUPPL. 1
Pagination
S18 - S25
Date published
2004
ISBN
09175040 (ISSN)
Keywords
Adult, alcohol consumption, Alcohol Drinking, All-cause mortality, article, cohort analysis, Cohort Studies, drinking behavior, Female, health survey, Health Surveys, human, Humans, Japan, Life Style, lifestyle, male, Middle Aged, mortality, proportional hazards model, Proportional Hazards Models, prospective cohort study, risk factor, Risk Factors
Abstract
Background: We examined the association between alcohol consumption and all-cause mortality in Japanese men and women. Methods: From June through August 1990, a total of 39,076 subjects (20,660 men and 18,416 women) in 14 municipalities of Miyagi Prefecture in rural northern Japan (40-64 years of age) completed a self-administered questionnaire that included information about alcohol consumption and various health habits. During 11 years of follow-up, we identified 1,879 deaths (1,335 men and 544 women). We used Cox proportional-hazards regression to estimate relative risk (RR) of all-cause mortality according to categories of alcohol consumption and to adjust for age, education, marital status, past histories of chronic diseases, body mass index, smoking, walking and dietary variables. Results: Among men, the risk for all-cause mortality was significantly higher in past drinkers than never-drinkers (multivariate RR, 1.86; 95% confidence interval [CI], 1.50-2.29). There was a dose-response association between alcohol consumption and the risk of all-cause mortality among current drinking men: multivariate RRs in reference to never-drinkers (95% CI) were 1.10 (0.90-1.33), 1.17 (0.96-1.42), 1.16 (0.96-1.40), and 1.62 (1.32-1.99) in current drinkers who consumed less than 22.8 g, 22.8-45.5 g, 45.6-68.3 g, and 68.4 g or more alcohol per day, respectively (P for trend<0.001). Similar association was observed among women (P for trend=0.005). Conclusions: The results indicated that alcohol consumption tended to be associated with linear increase in risk of all-cause mortality among Japanese men and women, and the association was remarkable for younger men. Copyright