Search resultsAlcohol consumption and the gastrointestinal tract
Title
Alcohol consumption and the gastrointestinal tract
Publication type
Journal Article
Year of Publication
2002
Authors
Journal
Israel Medical Association Journal
Volume
4
Issue
3
Pagination
200 - 202
Date published
2002
ISBN
15651088 (ISSN)
Keywords
alcohol, alcohol consumption, Alcohol Drinking, alcoholic beverage, Alcohols, antibacterial activity, antioxidant activity, bactericidal activity, Biological organs, Biomedical engineering, concentration (parameters), disinfection, Drug abuse, Drug products, enzyme activity, Esophagus, esophagus motility, Ethanol, France, Gastric Acid, Gastritis, gastrointestinal absorption, gastrointestinal disease, gastrointestinal infection, Gastrointestinal Motility, gastrointestinal mucosa, Gastrointestinal Neoplasms, Gastrointestinal Tract, gastrointestinal tumor, Helicobacter pylori, human, Humans, Intestinal Absorption, Liver, morbidity, mortality, nonhuman, Pancreas, pancreas insufficiency, Peptic Ulcer, polyphenol derivative, resveratrol, review, rutoside, Salmonella enteritidis, Shigella sonnei, Spain, stomach, stomach acid secretion, stomach motility, Toxic effects, toxicity testing, tumor growth, United States, wine
Abstract
Alcohol is one of the most commonly abused drugs, with a per capita consumption of approximately 10 L pure ethanol per year in the United States and even higher in Spain and France. In terms of mortality, the effect of alcohol on the liver and the pancreas is probably more significant than on the tubular gastrointestinal tract. However, alcohol is a very important cause of morbidity in the tubular gastrointestinal tract. Alcohol influences the motility in the esophagus, stomach and small bowel and has direct effects on the mucosa of the upper tract. While the stimulation of gastric acid secretion is inversely correlated with the alcohol concentration of the beverage, a direct pathogenetic role in peptic ulcer disease has not been demonstrated. Some alcohols, like red wine, have been shown to possess an anti-Helicobacter pylori effect. Alcohol also has a role in the development of tumors of the gastrointestinal tract.