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Title

Effects of alcohol on esophagus and stomach

Publication type

Journal Article

Year of Publication

2000

Authors

Teyssen, S., Singer, M.V.

Journal

Verdauungskrankheiten

Volume

Issue

Pagination

228 - 239

Date published

2000

ISBN

0174738X (ISSN)

Keywords

alcohol, alcohol consumption, Alcoholic Beverages, Barrett esophagus, Boerhaave syndrome, chronic gastritis, Esophagus, esophagus disease, Ethanol, human, Humans, Mallory Weiss syndrome, neutrophil, pathophysiology, Peptic Ulcer, review, stomach, stomach carcinoma, stomach disease

Abstract

The consumption of alcoholic beverages (i.e. ethanol) has many effects on the esophagus and stomach in healthy humans and alcoholics. Some of them are reversible, such as alcohol-associated motility disorders, reflux esophagitis and acute (hemorrhagic) gastritis. Pathophysiologically, damaging of the gastric mucosal barrier, release of inflammatory mediators, and activation of neutrophils are involved in the mediation of the ethanol-induced mucosal injury. In chronic alcohol abusers ethanol can induce directly and indirectly irreversible organic lesions such as carcinoma of the esophagus. The importance of chronic alcohol consumption concerning to the incidence of Barrett's syndrome, Mallory-Weiss syndrome, Boerhave's syndrome, peptic ulcer disease, chronic gastritis and gastric cancer is discussed.

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