Moderate alcohol consumption and waiting time to pregnancy
Title
Moderate alcohol consumption and waiting time to pregnancy
Publication type
Journal Article
Year of Publication
2001
Authors
Journal
Human Reproduction
Volume
16
Issue
12
Pagination
2705 - 2709
Date published
2001
ISBN
02681161 (ISSN)
Keywords
Adult, Age Factors, alcohol, alcohol consumption, Alcohol Drinking, article, Birth cohort, body mass, clinical observation, cohort analysis, Cohort Studies, controlled study, Denmark, drinking behavior, Fecundity, Female, fertility, human, Humans, Infertility, Female, medical research, obesity, Odds Ratio, outcomes research, parity, Pregnancy, Risk, second trimester pregnancy, self report, smoking, statistical analysis, time, Time Factors, Time to pregnancy
Abstract
Background: Recent research indicates that even a moderate consumption of alcohol in women trying to become pregnant is associated with longer waiting time to pregnancy. The findings, though, are based upon few observations. Methods: Self-reported data on alcohol intake and waiting time to pregnancy (0-2, 3-5, 6-12 and >12 months) was used for 39 612 pregnant women, recruited to the Danish National Birth Cohort within the first 24 weeks of pregnancy from 1997 to 2000. Main outcome measures were odds ratios (OR) for a prolonged waiting time to pregnancy according to alcohol intake. Results: In nulliparous women neither moderate nor high alcohol intake was related with longer waiting time to pregnancy compared with a low intake. In parous women, a modest association was seen only among those with an intake of >14 drinks per week (subfecundity OR 1.3; 95% confidence interval 1.0-1.7). Women who reported no alcohol intake had a slightly longer waiting time (subfecundity OR 1.2; 95% confidence interval 1.1-1.3) than women with a moderate intake of alcohol. Conclusions: Our findings do not corroborate recent results suggesting a marked reduction in fecundity associated with a moderate intake of alcohol.