Low to moderate alcohol consumption on serum vitamin D and other indicators of bone health in postmenopausal women in a controlled feeding study
Title
Low to moderate alcohol consumption on serum vitamin D and other indicators of bone health in postmenopausal women in a controlled feeding study
Publication type
Journal Article
Year of Publication
2014
Authors
Journal
European Journal of Clinical Nutrition
Volume
68
Issue
11
Pagination
1267 - 1270
Date published
2014
ISBN
09543007 (ISSN)
Keywords
25 hydroxyvitamin D, Adult, alcohol consumption, alkaline phosphatase, article, Asian, Black person, body mass, Bone health, bone specific alkaline phosphatase, bone turnover, Caucasian, clinical study, controlled study, deoxypyridinoline, diet restriction, feeding, Female, health, human, major clinical study, obesity, Osteocalcin, peptide, postmenopause, seasonal variation, unclassified drug, urinalysis, vitamin blood level, vitamin D
Abstract
The objective of this study was to evaluate the effect of 8 weeks of no alcohol, low (1 drink or 15 g/day) and moderate (2 drinks or 30 g/day) alcohol consumption on markers of bone health: fasting serum 25-hydroxy vitamin D (25(OH)D), osteocalcin (OC), bone-specific alkaline phosphatase (BSAP), urine deoxypyridinoline (DPD) and helical peptide (HP) in postmenopausal women (n=51). Compared with no alcohol, 1 or 2 drinks/day for 8 weeks had no significant impact on any of the bone markers. Within each alcohol group, obese women had significantly lower serum 25(OH)D and higher DPD concentrations than normal weight women. Season significantly affected the concentrations of serum 25(OH)D, but there was no significant interaction between alcohol and season on serum 25(OH)D concentrations. Low or moderate alcohol consumption for 8 weeks had no significant impact on markers of bone health in postmenopausal women.