Search resultsDo lifestyle choices explain the effect of alcohol on bone mineral density in women around menopause?
Title
Do lifestyle choices explain the effect of alcohol on bone mineral density in women around menopause?
Publication type
Journal Article
Year of Publication
2012
Authors
Journal
American Journal of Clinical Nutrition
Volume
95
Issue
5
Pagination
1261 - 1269
Date published
2012
ISBN
00029165 (ISSN)
Keywords
Adult, alcohol, alcohol consumption, Alcohol Drinking, Alcoholic Beverages, article, bone density, cluster analysis, Cross-Sectional Studies, cross-sectional study, diet, dietary intake, Exercise, Female, femur neck, Follow-Up Studies, fruit, fruit intake, Great Britain, Hormone Replacement Therapy, human, Humans, Life Style, lifestyle, lumbar spine, Lumbar Vertebrae, major clinical study, menopause, Middle Aged, physical activity, Risk Factors, smoking, vegetable, vegetable intake, Vegetables
Abstract
Background: Moderate alcohol consumption has been shown to be positively associated with increased bone mineral density (BMD). However, other lifestyle choices have also been shown to have an effect on bone health. Objective: The objective was to examine the association between alcohol intake and BMD in women around menopause in the United Kingdom and to determine whether any association is independent of other lifestyle choices. Design: A cross-sectional study design was used to examine the relation between alcohol intake and BMD in a cohort of 3218 women aged 50-62 y from the Aberdeen Prospective Osteoporosis Screening Study. Women were grouped into clusters according to their lifestyle choices. ANCOVA was used to examine the effect of categorized alcohol intake on BMD adjusted for cluster of lifestyle and other baseline covariates. The ANCOVA was repeated for different types of alcoholic beverage (eg, beer, liquor, and wine) separately. Results: Three lifestyle clusters were identified and were based on different levels of the following 3 factors: smoking pack-years, fruit and vegetable intakes, and physical activity. In the lifestyle-adjusted models, women who consumed >1 drink/d of alcohol had a significantly greater femoral neck BMD (P = 0.008) and lumbar spine BMD (P = 0.007) than did those who never consumed alcohol. For separate alcoholic drinks, only beer had a positive significant effect on lumbar spine BMD after adjustment for lifestyle (P = 0.005). Conclusion: Moderate alcohol intake appears to be positively associated with BMD independently of the type of lifestyle led by women around menopause.