Search resultsEffect of alcohol consumption on the prevalence of fatty liver disease
Title
Effect of alcohol consumption on the prevalence of fatty liver disease
Publication type
Journal Article
Year of Publication
2010
Authors
Journal
Acta Hepatologica Japonica
Volume
51
Issue
9
Pagination
501 - 507
Date published
2010
ISBN
04514203 (ISSN)
Keywords
abdominal obesity, Adult, alcohol, alcohol consumption, article, dyslipidemia, fatty liver, Female, glucose, glucose blood level, glucose intolerance, hepatitis B surface antigen, high density lipoprotein cholesterol, human, Life style disease, low density lipoprotein cholesterol, major clinical study, male, Nonalcoholic fatty liver disease, prevalence, risk factor, sex difference, triacylglycerol, Visceral fat obesity
Abstract
The effect of light to moderate alcohol consumption on the prevalence of obesity related fatty liver disease (FLD) is controversial. We analyzed 3185 individuals (male/female: 2243/939) who visited Oji General Hospital Health Checkup Center from January 2008 to December 2008. Multiple logistic regression was used to determine the association between alcohol consumption and FLD. Visceral fat obesity, impaired fasting glucose, and dyslipidemia were associated with increased Odds ratios for the fatty liver. On the other hand in men, minimal (<20 g) to moderate alcohol consumption (= 20 g and <40 g/day) was associated with decreased Odds ratio for fatty liver (FL). In women, however, alcohol consumption was not found to be associated with a decreased Odds ratio for FL. These results suggest that there is a sex difference in the effect of alcohol consumption on the prevalence of FLD and light to moderate alcohol consumption may have preventive effect on the developing obesity related FLD in men.