Alcohol consumption and risk of renal cell cancer: The NIH-AARP diet and health study
Title
Alcohol consumption and risk of renal cell cancer: The NIH-AARP diet and health study
Publication type
Journal Article
Year of Publication
2011
Authors
Journal
British Journal of Cancer
Volume
104
Issue
3
Pagination
537 - 541
Date published
2011
ISBN
00070920 (ISSN)
Keywords
Adult, Aged, alcohol, alcohol consumption, Alcohol Drinking, article, cancer risk, Carcinoma, Renal Cell, Cohort, diet, Female, human, Humans, kidney cancer, Kidney Neoplasms, major clinical study, male, priority journal, Prospective Studies, questionnaire, Questionnaires, renal cell cancer, Risk Factors
Abstract
Background: The effect of moderate to heavy drinking (>15 g per day) on renal cell cancer (RCC) risk is unclear. Method: The relationship between alcohol consumption and RCC was examined in the NIH-AARP Diet and Health Study (n=49 2187, 1814 cases). Results: Compared with >0 to <5 g per day of alcohol consumption, the multivariate relative risk (95% confidence intervals) for 15 to <30 and ≥30 g per day was, 0.75 (0.63-0.90) and 0.71 (0.59-0.85), respectively, in men and 0.67 (0.42-1.07) and 0.43 (0.22-0.84), respectively, in women. Conclusion: Alcohol consumption was inversely associated with RCC in a dose-response manner. The inverse association may be extended to ≥30 g per day of alcohol intake.