Search resultsRelationship between alcohol consumption and clinical manifestation of patients with fatty liver: A single-center study
Title
Relationship between alcohol consumption and clinical manifestation of patients with fatty liver: A single-center study
Publication type
Journal Article
Year of Publication
2011
Authors
Journal
Hepatobiliary and Pancreatic Diseases International
Volume
10
Issue
3
Pagination
276 - 279
Date published
2011
ISBN
14993872 (ISSN)
Keywords
Adult, Aged, alcohol, alcohol consumption, Alcohol Drinking, article, aspartate aminotransferase, Aspartate Aminotransferases, Aspartate transaminase, Biological Markers, Chi-Square Distribution, China, Clinical Enzyme Tests, clinical feature, controlled study, drinking behavior, fatty liver, Fatty Liver, Alcoholic, Female, gamma glutamyltransferase, Gamma-glutamyl transpeptidase, gamma-Glutamyltransferase, hemoglobin, Hemoglobins, human, Humans, laboratory test, long term exposure, major clinical study, male, Middle Aged, morbidity, pathogenesis, Predictive Value of Tests, Prognosis, protein blood level, risk assessment, Risk Factors, Time Factors, Up-Regulation
Abstract
BACKGROUND: Fatty liver is a common chronic liver disease worldwide. It is associated with an increasing morbidity in China in recent years. The aim of this study was to analyze the effect of drinking alcohol on the hemoglobin and biochemical values of patients with fatty liver. METHODS: We investigated the clinical and laboratory data of 669 patients with fatty liver. Of the 669 patients, 166 consumed alcohol more than 60 g per week for at least 2 years, and 503 did not have a history of long-term alcohol consumption. We further analyzed the relationship between alcohol consumption and clinical characteristics of these patients. RESULTS: The values of aspartate transaminase (AST), gamma-glutamyl transpeptidase (GGT), and hemoglobin in the long-term consumption group were significantly higher than those in the non long-term consumption group (P<0.05). In the patients without long-term alcohol consumption, the values of GGT and hemoglobin in patients with light alcohol consumption were significantly higher than those in non alcohol consumers (P<0.05). CONCLUSION: Alcohol consumption is associated with significantly increased values of AST, GGT, and hemoglobin in patients with fatty liver, suggesting their potential roles in hepatic steatosis.