Search resultsComorbidity of axis I and II mental disorders with schizophrenia and psychotic disorders: Findings from the national epidemiologic survey on alcohol and related conditions
Title
Comorbidity of axis I and II mental disorders with schizophrenia and psychotic disorders: Findings from the national epidemiologic survey on alcohol and related conditions
Publication type
Journal Article
Year of Publication
2009
Authors
Journal
Canadian Journal of Psychiatry
Volume
54
Issue
7
Pagination
477 - 486
Date published
2009
ISBN
07067437 (ISSN)
Keywords
Adolescent, Adult, Aged, Aged, 80 and over, Alcoholism, anxiety, article, Bipolar Disorder, Canada, comorbidity, controlled study, Cross-Sectional Studies, Depressive Disorder, Major, Diagnostic and Statistical Manual of Mental Disorders, DSM, epidemiology, Female, health practitioner, health survey, Health Surveys, human, Humans, income, major clinical study, male, marriage, mental disease, Mental Disorders, Middle Aged, mood, personality, personality disorder, Personality Disorders, prevalence, psychiatric diagnosis, psychosis, Psychotic Disorders, Psychotropic Drugs, quality of life, questionnaire, schizophrenia, self report, Socioeconomic Factors, substance abuse, Substance dependence, Substance-Related Disorders, Young Adult
Abstract
Objective: To examine the comorbidity of Axis I and II disorders within a community-based sample of adults with schizophrenia. Methods: The study was conducted using data from the National Epidemiologic Survey of Alcohol and Related Conditions. A diagnosis of schizophrenia was based on respondents' self-report that they had been diagnosed by a health professional with schizophrenia or a psychotic illness or episode (SPIE). Axis I disorders and Axis II personality disorders (PDs) were assessed using the Alcohol Use Disorders and Associated Disabilities Interview Schedule. Mental and physical quality of life were assessed using the Medical Outcomes Study Short Form 12 questionnaire. Results: The prevalence of SPIE was 0.9%. We used multiple logistic regression to examine the association between the presence and absence of SPIE in Axis I and II mental disorders. Each of the Axis I and II mental disorders examined were significantly associated with a diagnosis of SPIE after controlling for age, sex, education, marital status, and household income. Conclusions: Clinicians should be aware of the patterns and extent of psychiatric comorbidities that may exist in schizophrenia. Possible mechanisms of these associations are discussed.