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Long-term and short-term alcohol consumption and levels of C-reactive protein

Title
Long-term and short-term alcohol consumption and levels of C-reactive protein
Publication type
Journal Article
Year of Publication
2007
Authors
Raum, E., Gebhardt, K., Buchner, M., Schiltenwolf, M., Brenner, H.
Journal
International Journal of Cardiology
Volume
121
Issue
2
Pagination
224 - 226
Date published
2007
ISBN
01675273 (ISSN)
Keywords
Adult, alcohol, alcohol consumption, Alcohol Drinking, Alcoholism, article, C reactive protein, C-Reactive Protein, disease association, dose response, Female, Follow-Up Studies, human, Humans, inflammation, long term exposure, major clinical study, male, priority journal, time
Abstract
The association between alcohol consumption and CRP was evaluated in a longitudinal study among 72 middle aged adults for whom 572 repeated measurements of CRP were obtained. Short- and long-term alcohol consumption were analyzed using moving windows of average alcohol consumption levels to establish a dose-response relationship. To control for intra-individual dependence of measurements, generalised estimating equations were used. Average alcohol consumption during the last 12 months showed a clear U-shaped relationship with CRP-levels, with lowest levels found for moderate alcohol consumption of less than 16 g/day. For short-term alcohol consumption no association was found.
DOI
https://dx.doi.org/10.1016/j.ijcard.2006.08.104
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